Balanced Nuclear and Cytoplasmic Activities of EDS1 Are Required for a Complete Plant Innate Immune Response

@inproceedings{Garcia2010BalancedNA,
  title={Balanced Nuclear and Cytoplasmic Activities of EDS1 Are Required for a Complete Plant Innate Immune Response},
  author={Ana Victoria Garcia and Servane Blanvillain-Baufum{\'e} and Robin P. Huibers and Marcel Wiermer and Guangyong Li and Enrico Gobbato and Steffen Rietz and Jane E Parker},
  booktitle={PLoS pathogens},
  year={2010}
}
An important layer of plant innate immunity to host-adapted pathogens is conferred by intracellular nucleotide-binding/oligomerization domain-leucine rich repeat (NB-LRR) receptors recognizing specific microbial effectors. Signaling from activated receptors of the TIR (Toll/Interleukin-1 Receptor)-NB-LRR class converges on the nucleo-cytoplasmic immune regulator EDS1 (Enhanced Disease Susceptibility1). In this report we show that a receptor-stimulated increase in accumulation of nuclear EDS1… CONTINUE READING
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