Balance of pro- and anti-inflammatory cytokines correlates with outcome of acute experimental Pseudomonas aeruginosa keratitis.

@article{Thakur2002BalanceOP,
  title={Balance of pro- and anti-inflammatory cytokines correlates with outcome of acute experimental Pseudomonas aeruginosa keratitis.},
  author={Archana N. Thakur and M L Xue and Fiona Jane Stapleton and Andrew R. Lloyd and Denis Wakefield and Mark Willcox},
  journal={Infection and immunity},
  year={2002},
  volume={70 4},
  pages={2187-97}
}
The purpose of this study was to elucidate the expression of pro- and anti-inflammatory cytokines in mouse corneas infected with Pseudomonas aeruginosa. Three bacterial strains (invasive, cytotoxic, or CLARE [contact lens-induced acute red eye]) which have recently been shown to produce distinct patterns of corneal disease in the mouse were used. The left mouse (BALB/c) corneas were scarified and infected with 2 x 10(6) CFU of one of the three P. aeruginosa strains, while right eyes served as… CONTINUE READING

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