Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus.

@article{Wang2016BaicalinAI,
  title={Baicalin alleviates ischemia-induced memory impairment by inhibiting the phosphorylation of CaMKII in hippocampus.},
  author={Peng Wang and Yonggang Cao and Juan Yu and Ruxia Liu and Bing Bai and Hanping Qi and Qianlong Zhang and Wenguang Guo and Hongbo Jin and Lihui Qu},
  journal={Brain research},
  year={2016},
  volume={1642},
  pages={95-103}
}
Baicalin has a significant neuroprotective effect in stroke. However, the mechanism remains unclear. This study was to reveal the mechanisms by which baicalin protected hippocampal neurons and improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbil. In the present study, the Morris water maze test showed that baicalin significantly improved learning and memory impairment after global cerebral ischemia/reperfusion in gerbils. Laser scanning confocal… CONTINUE READING

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