Corpus ID: 52906540

Baicalein and U 0126 suppress human breast cancer cell line MCF-7 through regulating MAPK signaling pathway

  title={Baicalein and U 0126 suppress human breast cancer cell line MCF-7 through regulating MAPK signaling pathway},
  author={H. An and X. Yu and C. Xiang and Yujiao Zhang and Jiyi Xia and Yongzhou Wang},
Backgroud: Baicalein is a member of active falvonoids compounds with anti-bacterial, anti-inflammatory, and anti-infection effect. The aim of the present study was to explore the inhibition effect of baicalein on human breast cancer cell line MCF-7 and the related mechanism. Methods: MCF-7 cells were treated by different concentrations of baicalein with or without U0126. Cell viability was tested by CCK8. Cell cycle was determined by flow cytometry. Cell migration was measured by wound healing… Expand
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