Corpus ID: 201719941

Baicalein 6-methy ether 7-glucoside induced apoptosis in HeLa cells via caspase dependent pathway

  title={Baicalein 6-methy ether 7-glucoside induced apoptosis in HeLa cells via caspase dependent pathway},
  author={Z. Guan and X. Wang and S. Jiang and D. An and J. Li and Shui Yu and L. Ye},
Background: Baicalin is a traditional herbal medicine and widely used in the pharmaceutical, cosmetic, and food industries due to its biological functions. In the present study, we report that an analogue of baicalin, baicalein 6-methy ether 7-glucoside (BG), is significantly more toxic to HeLa cells than baicalin and investigate the potential molecular mechanisms. Methods: The effects of baicalin and BG on cell viabilities in vitro were quantified by CCK-8 assay. Apoptosis of HeLa cells… Expand
1 Citations

Figures from this paper


Effects and Mechanism of Baicalin on Apoptosis of Cervical Cancer HeLa Cells In-vitro
  • 20
  • PDF
Baicalin down regulates the expression of TLR4 and NFkB-p65 in colon tissue in mice with colitis induced by dextran sulfate sodium.
  • 44
  • PDF
Baicalein and baicalin are potent inhibitors of angiogenesis: Inhibition of endothelial cell proliferation, migration and differentiation
  • 123
Polypeptide Fraction from Arca subcrenata Induces Apoptosis and G2/M Phase Arrest in HeLa Cells via ROS-Mediated MAPKs Pathways
  • 12
  • PDF
Baicalin induces human mucoepidermoid carcinoma Mc3 cells apoptosis in vitro and in vivo
  • 39
Baicalin attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-oxidative and anti-apoptotic pathways
  • 134
The protective effect of baicalin against renal ischemia-reperfusion injury through inhibition of inflammation and apoptosis
  • M. Lin, L. Li, +4 authors T. Zhu
  • Medicine
  • BMC Complementary and Alternative Medicine
  • 2014
  • 87
  • PDF
Antiviral activity of baicalin against influenza virus H1N1-pdm09 is due to modulation of NS1-mediated cellular innate immune responses.
  • 63
  • PDF