Bag-1M is a component of the in vivo DNA-glucocorticoid receptor complex at hormone-regulated promoter.

@article{Hong2008Bag1MIA,
  title={Bag-1M is a component of the in vivo DNA-glucocorticoid receptor complex at hormone-regulated promoter.},
  author={Wei Hong and Aria Baniahmad and Yunde Liu and Huiqiang Li},
  journal={Journal of molecular biology},
  year={2008},
  volume={384 1},
  pages={22-30}
}
Molecular chaperones and cochaperones are known to participate in nuclear receptor-mediated gene expression in addition to providing the appropriate conformation for hormone binding. It has been reported that Bag-1M (Bcl-2 associated athanogene 1M) downregulates the transactivation function of the glucocorticoid receptor (GR). Here, we demonstrate that Bag… CONTINUE READING