Bafilomycins produced by an endophytic actinomycete Streptomyces sp. YIM56209

Abstract

Bafilomycins (Figure 1), macrolide antibiotics with a 16-membered lactone ring as their defining structural scaffold, are produced by a variety of streptomycetes.1–5 These macrolides exhibit a variety of biological activities, including antitumor,6 antifungal,7 antiparasitic8 and immunosuppressant activities.9 In particular, bafilomycin A1 is an extremely… (More)
DOI: 10.1038/ja.2010.147

Topics

4 Figures and Tables

Slides referencing similar topics