Baculovirus-mediated trans-epithelial transport of proteins in infected caterpillars.

  title={Baculovirus-mediated trans-epithelial transport of proteins in infected caterpillars.},
  author={Mikl{\'o}s S{\'a}rv{\'a}ri and P{\'e}ter Z{\'a}vodszky and Kinga Moln{\'a}r and P L{\^o}w and Mikl{\'o}s Sass},
  journal={The Journal of general virology},
  volume={78 ( Pt 4)},
Baculovirus-mediated abnormal protein trafficking was studied in infected caterpillars by using heterologous proteins. The gene for human complement C1r was expressed in larvae of Mamestra brassicae by a recombinant Autographa californica nuclear polyhedrosis virus (AcMNPV) vector. By following the time-course of recombinant C1r distribution among various tissues, cell types and cell organelles, we concluded that the dominant site of recombinant protein synthesis was the fat body, although some… CONTINUE READING