Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell death.

Abstract

Members of the inhibitor of apoptosis (iap) gene family prevent programmed cell death induced by multiple signals in diverse organisms, suggesting that they act at a conserved step in the apoptotic pathway. To investigate the molecular mechanism of iap function, we expressed epitope-tagged Op-iap, the prototype viral iap from Orgyia pseudotsugata nuclear… (More)

Topics

9 Figures and Tables

Cite this paper

@article{Manji1997BaculovirusIO, title={Baculovirus inhibitor of apoptosis functions at or upstream of the apoptotic suppressor P35 to prevent programmed cell death.}, author={Gulam A Manji and R R Hozak and Douglas J Lacount and Paul D Friesen}, journal={Journal of virology}, year={1997}, volume={71 6}, pages={4509-16} }