Baculovirus expression and antigenic characterization of the capsid proteins of three Norwalk-like viruses

@article{Jiang2002BaculovirusEA,
  title={Baculovirus expression and antigenic characterization of the capsid proteins of three Norwalk-like viruses},
  author={Xi Jiang and W. M. Zhong and Tibor Farkas and Paul W Huang and Nouansy K Wilton and Elizabeth Barrett and Dorcas Fulton and Rebecca N. Morrow and David O. Matson},
  journal={Archives of Virology},
  year={2002},
  volume={147},
  pages={119-130}
}
 Human caliciviruses (HuCVs) are antigenically diverse. The antigenic relationships among different HuCVs have been difficult to study because HuCVs cannot be passaged in the laboratory. In this study, we describe cloning, sequencing and expression of the viral capsid proteins of three HuCVs that were identified in outbreaks of acute gastroenteritis in Virginia in 1997–1998. Yields of the capsid proteins similar to previously expressed recombinant Norwalk virus were obtained using the… CONTINUE READING

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