Baculovirus entry into human hepatoma cells.

  title={Baculovirus entry into human hepatoma cells.},
  author={Heli Matilainen and Johanna Rinne and L Gilbert and Varpu S Marjom{\"a}ki and Hilkka Reunanen and Christian Oker-Blom},
  journal={Journal of virology},
  volume={79 24},
Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a prototype member of the Baculoviridae family, has gained increasing interest as a potential vector candidate for mammalian gene delivery applications. AcMNPV is known to enter both dividing and nondividing mammalian cell lines in vitro, but the mode and kinetics of entry as well as the intracellular transport of the virus in mammalian cells is poorly understood. The general objective of this study was to characterize the entry… CONTINUE READING
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