Baculovirus VP80 protein and the F-actin cytoskeleton interact and connect the viral replication factory with the nuclear periphery.

@article{Marek2011BaculovirusVP,
  title={Baculovirus VP80 protein and the F-actin cytoskeleton interact and connect the viral replication factory with the nuclear periphery.},
  author={Martin Marek and O. -W. Merten and Lionel Galibert and Just M. Vlak and Monique M. van Oers},
  journal={Journal of virology},
  year={2011},
  volume={85 11},
  pages={5350-62}
}
Recently, we showed that the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) VP80 protein is essential for the formation of both virion types, budded virus (BV) and occlusion-derived virus (ODV). Deletion of the vp80 gene did not affect assembly of nucleocapsids. However, these nucleocapsids were not able to migrate from the virogenic stroma to the nuclear periphery. In the current paper, we constructed a baculovirus recombinant with enhanced-green fluorescent protein (EGFP… CONTINUE READING
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