Bacteroides fragilis-stimulated interleukin-10 contains expanding disease.

@article{CohenPoradosu2011BacteroidesFI,
  title={Bacteroides fragilis-stimulated interleukin-10 contains expanding disease.},
  author={Ronit Cohen-Poradosu and Rachel M McLoughlin and Jerry Lee and Dennis L Kasper},
  journal={The Journal of infectious diseases},
  year={2011},
  volume={204 3},
  pages={
          363-71
        }
}
Commensal symbionts may become pathogens upon escaping their habitat. In the gut, Bacteroides fragilis protects against colitis through induction of interleukin 10 (IL-10) by CD4(+) T cells. When intestinal integrity is disrupted, B. fragilis and colonic contents escape into the peritoneum, causing abscesses and bacteremia. Whether the virulence mechanisms employed by B. fragilis during infections differ from those employed for symbiosis during commensalism is unknown. We demonstrate T cell… CONTINUE READING

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