Bacteroides (Porphyromonas) gingivalis fimbriae activate mouse peritoneal macrophages and induce gene expression and production of interleukin-1

@article{Hanazawa1991BacteroidesG,
  title={Bacteroides (Porphyromonas) gingivalis fimbriae activate mouse peritoneal macrophages and induce gene expression and production of interleukin-1},
  author={Shigemasa Hanazawa and Yukio Murakami and Kimiharu Hirose and Shigeru Amano and Yoshihiro Ohmori and Hiroshi Higuchi and Shigeo Kitano},
  journal={Infection and Immunity},
  year={1991},
  volume={59},
  pages={1972 - 1977}
}
The purpose of this study was to examine whether Bacteroides (Porphyromonas) gingivalis fimbriae, an important structure involved in attachment of the bacteria to periodontal tissues, activate macrophages and subsequently induce gene expression and production of interleukin-1 (IL-1) in the cells. The fimbriae increased glucose consumption and lysozyme activity in BALB/c macrophages, both criteria of macrophage activation of peritoneal macrophages, in a dose-dependent fashion. A marked increase… 

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