Bacteriostatic and bactericidal modes of action of bis(tributyltin)oxide on Legionella pneumophila.

@article{Soracco1983BacteriostaticAB,
  title={Bacteriostatic and bactericidal modes of action of bis(tributyltin)oxide on Legionella pneumophila.},
  author={R J Soracco and Daniel H. Pope},
  journal={Applied and environmental microbiology},
  year={1983},
  volume={45 1},
  pages={48-57}
}
The modes of action of bis(tributyltin)oxide (TBTO) doses between 1 X 10(4) and 6 X 10(7) molecules per cell on a single environmental isolate of Legionella pneumophila were studied by monitoring the following parameters: (i) growth, (ii) cell viability, (iii) 14C-amino acid incorporation, (iv) 14CO2 production from 14C-amino acids, (v) [3H]uridine incorporation, (vi) [3H]thymidine incorporation, (vii) oxygen consumption, (viii) cellular ATP levels, and (ix) adenylate energy charge. The amount… CONTINUE READING