Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases

  title={Bacteriophage therapy: a revitalized therapy against bacterial infectious diseases},
  author={S. Matsuzaki and M. Rashel and Jumpei Uchiyama and Shingo Sakurai and T. Ujihara and M. Kuroda and M. Ikeuchi and T. Tani and M. Fujieda and H. Wakiguchi and S. Imai},
  journal={Journal of Infection and Chemotherapy},
  • S. Matsuzaki, M. Rashel, +8 authors S. Imai
  • Published 2005
  • Medicine, Biology
  • Journal of Infection and Chemotherapy
  • Bacteriophage (phage) therapy involves using phages or their products as bioagents for the treatment or prophylaxis of bacterial infectious diseases. Much evidence in support of the effectiveness of phage therapy against bacterial infectious diseases has accumulated since 1980 from animal model studies conducted in Western countries. Reports indicate that appropriate administration of living phages can be used to treat lethal infectious diseases caused by gram-negative bacteria, such as… CONTINUE READING
    342 Citations
    Phage for Biocontrol
    • 3
    Bacteriophages and Phage-Derived Proteins – Application Approaches
    • 89
    • PDF
    Lysin Therapy for Staphylococcus aureus and Other Bacterial Pathogens.
    • V. Fischetti
    • Biology, Medicine
    • Current topics in microbiology and immunology
    • 2017
    • 17
    Bacteriophages as an alternative strategy for fighting biofilm development.
    • 73
    • Highly Influenced
    • PDF


    Therapy of Experimental Pseudomonas Infections with a Nonreplicating Genetically Modified Phage
    • 156
    • Highly Influential
    • PDF
    Long-circulating bacteriophage as antibacterial agents.
    • C. Merril, B. Biswas, +4 authors S. Adhya
    • Biology, Medicine
    • Proceedings of the National Academy of Sciences of the United States of America
    • 1996
    • 404
    • PDF
    Removal of Group B Streptococci Colonizing the Vagina and Oropharynx of Mice with a Bacteriophage Lytic Enzyme
    • 200
    • PDF
    Bacteriophages show promise as antimicrobial agents.
    • 305
    Potential of the Polyvalent Anti-Staphylococcus Bacteriophage K for Control of Antibiotic-Resistant Staphylococci from Hospitals
    • 197
    • PDF
    Phage lytic enzymes as therapy for antibiotic-resistant Streptococcus pneumoniae infection in a murine sepsis model.
    • 178
    • PDF
    Treatment of experimental infections of mice with bacteriophages.
    • 164
    • PDF