Bacteriophage T7 protein kinase phosphorylates RNase E and stabilizes mRNAs synthesized by T7 RNA polymerase.

@article{Marchand2001BacteriophageTP,
  title={Bacteriophage T7 protein kinase phosphorylates RNase E and stabilizes mRNAs synthesized by T7 RNA polymerase.},
  author={Isabelle Marchand and Allen W. Nicholson and Marc Dreyfus},
  journal={Molecular microbiology},
  year={2001},
  volume={42 3},
  pages={767-76}
}
The T7 protein encoded by the early gene 0.7 exhibits bifunctional activity. Whereas its C-terminal one-third participates in host transcription shut-off, the N-terminal two-thirds bears a protein kinase ('PK') activity that can phosphorylate a number of host proteins in addition to itself. Here, we show that, when PK is expressed in uninfected Escherichia… CONTINUE READING