Bacteriophage P1 Ban protein is a hexameric DNA helicase that interacts with and substitutes for Escherichia coli DnaB.

@article{Lemonnier2003BacteriophagePB,
  title={Bacteriophage P1 Ban protein is a hexameric DNA helicase that interacts with and substitutes for Escherichia coli DnaB.},
  author={Marc Lemonnier and G{\"u}nter Ziegelin and Tobias Reick and Ana Mu{\~n}oz G{\'o}mez and Ram{\'o}n D{\'i}az-Orejas and Erich Lanka},
  journal={Nucleic acids research},
  year={2003},
  volume={31 14},
  pages={3918-28}
}
Since the ban gene of bacteriophage P1 suppresses a number of conditionally lethal dnaB mutations in Escherichia coli, it was assumed that Ban protein is a DNA helicase (DnaB analogue) that can substitute for DnaB in the host replication machinery. We isolated and sequenced the ban gene, purified the product, and analysed the function of Ban protein in… CONTINUE READING
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