Bacteriophage K antimicrobial-lock technique for treatment of Staphylococcus aureus central venous catheter-related infection: a leporine model efficacy analysis.

@article{Lungren2014BacteriophageKA,
  title={Bacteriophage K antimicrobial-lock technique for treatment of Staphylococcus aureus central venous catheter-related infection: a leporine model efficacy analysis.},
  author={Matthew P. Lungren and Rodney M. Donlan and Ravi J Kankotia and Ben E. Paxton and Isaac D. Falk and Diana L. Christensen and Charles Y Kim},
  journal={Journal of vascular and interventional radiology : JVIR},
  year={2014},
  volume={25 10},
  pages={
          1627-32
        }
}
PURPOSE To determine whether a bacteriophage antimicrobial-lock technique can reduce bacterial colonization and biofilm formation on indwelling central venous catheters in a rabbit model. MATERIALS AND METHODS Cuffed central venous catheters were inserted into the jugular vein of female New Zealand White rabbits under image guidance. Catheters were inoculated for 24 hours with broth culture of methicillin-sensitive Staphylococcus aureus. The inoculum was aspirated, and rabbits were randomly… CONTINUE READING
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