Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents.

@article{Citron2007BacteriologyOM,
  title={Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents.},
  author={Diane M. Citron and Ellie J. C. Goldstein and C. Vreni Merriam and Benjamin A. Lipsky and Murray A Abramson},
  journal={Journal of clinical microbiology},
  year={2007},
  volume={45 9},
  pages={2819-28}
}
As part of a United States-based multicenter clinical trial, conducted from 2001 to 2004, that compared ertapenem to piperacillin-tazobactam for the treatment of moderate-to-severe diabetic foot infections (DFIs), we obtained 454 pretreatment specimens from 433 patients. After debridement, the investigators collected wound specimens, mostly by curettage or biopsy, and sent them to the R. M. Alden Research Laboratory for aerobic and anaerobic culture. Among the 427 positive cultures, 83.8% were… CONTINUE READING