[Bacteriological investigation on an outbreak of acute enteritis associated with verotoxin-producing Escherichia coli O111:H-].

Abstract

An outbreak of acute enteritis in children aged one to thirty-three months occurred from June 10th to 23rd, 1986, at a private orphanage in Matsuyama City. Twenty-two out of 23 children suffered from diarrhea. Nine of the 22 children excreted bloody stool. Fever and vomiting were observed with a few patients. One of them, a 33-month-old girl, developed hemolytic uremic syndrome, and died twelve days after the admission. Escherichia coli O111:H- was isolated from fecal specimens of 7 out of 15 patients. The culture filtrate of the isolate caused fluid accumulation in ligated ileal loops in a rabbit, and was lethal to mice. It was found that all isolates produced two kinds of Vero toxins (VT1 and VT2, or shiga-like toxin I and II). The amount of VT2 produced in vitro was about 10 times more than that of VT1.

Cite this paper

@article{Tanaka1989BacteriologicalIO, title={[Bacteriological investigation on an outbreak of acute enteritis associated with verotoxin-producing Escherichia coli O111:H-].}, author={Hirokazu Tanaka and M Ohseto and Y. Yamashita and Nobuo Shinohara and Hiroshi Inoue and Yu Sasaki and Yasuharu Kakihara and Taiji Tsukamoto and Takashi Yutsudo and Yuzaburo Oku}, journal={Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases}, year={1989}, volume={63 10}, pages={1187-94} }