Bacteriologic and clinical efficacy of oral gatifloxacin for the treatment of recurrent/nonresponsive acute otitis media: an open label, noncomparative, double tympanocentesis study.

@article{Leibovitz2003BacteriologicAC,
  title={Bacteriologic and clinical efficacy of oral gatifloxacin for the treatment of recurrent/nonresponsive acute otitis media: an open label, noncomparative, double tympanocentesis study.},
  author={Eugene Leibovitz and Lolita Piglansky and Simon Raiz and David Greenberg and Kamal A. Hamed and J M Ledeine and Joseph J Press and Alberto Leiberman and Roger M Echols and Phillip F Pierce and Michael R. Jacobs and Ron Dagan},
  journal={The Pediatric infectious disease journal},
  year={2003},
  volume={22 11},
  pages={943-9}
}
BACKGROUND Gatifloxacin is an 8-methoxyfluoroquinolone with good activity against respiratory pathogens. OBJECTIVES To document the bacteriologic and clinical efficacy of gatifloxacin in recurrent/nonresponsive acute otitis media (AOM). METHODS One hundred sixty patients 6 to 48 months of age with recurrent/nonresponsive AOM received gatifloxacin suspension (10 mg/kg once daily for 10 days). Recurrent AOM was defined as > or =3 AOM episodes during the previous 6 months or > or =4 AOM… CONTINUE READING

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