Bactericidal Activity of Wet Cerumen

@article{Stone1984BactericidalAO,
  title={Bactericidal Activity of Wet Cerumen},
  author={M Stone and Robert S. Fulghum},
  journal={Annals of Otology, Rhinology \& Laryngology},
  year={1984},
  volume={93},
  pages={183 - 186}
}
The viable populations of seven species of bacteria were reduced 17% to 99% by treatment with a 3% suspension of human cerumen of the soft or “wet” type. Species tested for susceptibility to cerumen were Staphylococcus aureus, Staphylococcus epidermidis. Streptococcus pyogenes, Propionibacterium acnes, Corynebacterium spp, Escherichia coli, and Serratia marcescens. The reduction depended upon the species of bacterium and the age of the culture. Pathogenic species appeared to be more susceptible… 

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Isolated bacteria from cerumen of healthy subjects were different in comparison to those of acute otitis externa patients, and there was significant association between colony count and actue otitisExterna status.

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The results have demonstrated that the antimicrobial impact of ear wax suspension revealed exceptionally huge against Bacillus followed by Salmonella and Klebsiella with similarly impact while there is no antimicrobial effect of the suspension on both Staph and Pseudomonas.

Studies of the microenvironment and microflora of the canine external ear canal

TLDR
Marked variation was found in the distribution of sebaceous and apocrine glands in the aural integument in healthy ears and those with otitis, and the numbers of microorganisms found in cerumen cytological smears appear to be correlated to the growth density of microbial colonies on culture plates.
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