Bacterial tyrosine kinases: novel targets for antibacterial therapy?

  title={Bacterial tyrosine kinases: novel targets for antibacterial therapy?},
  author={Alain J. Cozzone},
  journal={Trends in microbiology},
  volume={17 12},
The resistance of pathogenic bacteria to current antibiotics has become a crucial public health problem. To combat this resistance, there is a constant need for antibacterial drugs with new modes of action on therapeutic targets. Recent data have shown that a variety of cellular processes essential for bacterial survival and virulence are regulated by the phosphorylation of certain endogenous proteins catalyzed by specific tyrosine kinases. In this article, I highlight a selection of recent… CONTINUE READING

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