Bacterial-type DNA holliday junction resolvases in eukaryotic viruses.

@article{Garcia2000BacterialtypeDH,
  title={Bacterial-type DNA holliday junction resolvases in eukaryotic viruses.},
  author={Alonzo D. Garcia and L. Aravind and Eugene V. Koonin and Bernard Moss},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 16},
  pages={8926-31}
}
Homologous DNA recombination promotes genetic diversity and the maintenance of genome integrity, yet no enzymes with specificity for the Holliday junction (HJ)-a key DNA recombination intermediate-have been purified and characterized from metazoa or their viruses. Here we identify critical structural elements of RuvC, a bacterial HJ resolvase, in uncharacterized open reading frames from poxviruses and an iridovirus. The putative vaccinia virus resolvase was expressed as a recombinant protein… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 35 extracted citations

Mapping vaccinia virus DNA replication origins at nucleotide level by deep sequencing.

Proceedings of the National Academy of Sciences of the United States of America • 2015
View 1 Excerpt

Poxvirus DNA replication.

Cold Spring Harbor perspectives in biology • 2013
View 4 Excerpts

References

Publications referenced by this paper.

Cold Spring Harbor Symp

M. Merchlinsky, B. Moss
Quant . Biol . • 1982

Similar Papers

Loading similar papers…