Bacterial translocation, endotoxaemia and apoptosis following Pringle manoeuvre in rats.

@article{Filos2004BacterialTE,
  title={Bacterial translocation, endotoxaemia and apoptosis following Pringle manoeuvre in rats.},
  author={Kriton S. Filos and Ioannis Kirkilesis and Iris Spiliopoulou and Chrisoula D. Scopa and Vassiliki N. Nikolopoulou and Gregorios P. Kouraklis and Constantine E. Vagianos},
  journal={Injury},
  year={2004},
  volume={35 1},
  pages={35-43}
}
BACKGROUND Intraoperative occlusion of the hepatoduodenal ligament (Pringle manoeuvre (Pm)) is often employed for the reduction of blood loss during liver surgery. No data exist to date on the effects of Pm on mucosal barrier dysfunction, systemic bacterial translocation (BT), endotoxaemia and apoptosis. MATERIALS AND METHODS Sixty-five male Wistar rats in three groups: I (n=25) controls, II (n=20) sham operation, III (n=20) occlusion of the hepatoduodenal ligament (Pm). Tissue samples from… CONTINUE READING