Bacterial transformation: distribution, shared mechanisms and divergent control

  title={Bacterial transformation: distribution, shared mechanisms and divergent control},
  author={C. Johnston and B. Martin and G. Fichant and P. Polard and J. Claverys},
  journal={Nature Reviews Microbiology},
  • C. Johnston, B. Martin, +2 authors J. Claverys
  • Published 2014
  • Biology, Medicine
  • Nature Reviews Microbiology
  • Natural bacterial transformation involves the internalization and chromosomal integration of DNA and has now been documented in ∼80 species. Recent advances have established that phylogenetically distant species share conserved uptake and processing proteins but differ in the inducing cues and regulatory mechanisms that are involved. In this Review, we highlight divergent and common principles that govern the transformation process in different bacteria. We discuss how this cumulative knowledge… CONTINUE READING
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