Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals.

@article{Piel2006BacterialSP,
  title={Bacterial symbionts: prospects for the sustainable production of invertebrate-derived pharmaceuticals.},
  author={J{\"o}rn Piel},
  journal={Current medicinal chemistry},
  year={2006},
  volume={13 1},
  pages={
          39-50
        }
}
  • Jörn Piel
  • Published 2006 in Current medicinal chemistry
Invertebrate animals, such as sponges, tunicates and bryozoans, are among the most important sources of biomedically relevant natural products. However, as these animals generally contain only low quantities of the compounds, further pharmacological development is in most cases difficult. There is increasing evidence that many metabolites, in particular polyketides and nonribosomally synthesized peptides, are not produced by the animals themselves but by associated bacterial symbionts. This… CONTINUE READING

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