336 Citations
Bacterial meningitis in childhood.
- Medicine, BiologyAdvances in experimental medicine and biology
- 2011
In the last two decades widespread introduction of highly effective conjugate vaccines against these pathogens in many industrialised countries has led to a significant reduction in the incidence of bacterial meningitis, although there is still a substantial global burden of disease.
Bacterial meningitis in children.
- Medicine, Biology
- 2007
A significant reduction of the numbers of bacterial meningitis caused by Haemophilus influinzae type B species is found in children beyond the neonatal period.
Bacterial Meningitis
- MedicineDrugs
- 2012
Clinical studies have demonstrated the benefit of adjunctive dexamethasone in infants and children with Haemophilus influenzae type B meningitis, and adults with pneumococcal meneditis, in which mortality and adverse outcome are reduced.
Paediatric meningitis: Clinical features and diagnosis
- Medicine
- 2009
Children who contract meningitis during the first year of life have a 15.6% chance of developing a permanent, severe or moderately severe disability by the time they reach five years of age.
Diagnosis, initial management, and prevention of meningitis.
- MedicineAmerican family physician
- 2010
Empiric antimicrobial therapy based on age and risk factors must be started promptly in patients with bacterial meningitis and should not be delayed, even if a lumbar puncture cannot be performed because results of a computed tomography scan are pending or because the patient is awaiting transfer.
Bacteremia in children: epidemiology, clinical diagnosis and antibiotic treatment
- Medicine, BiologyExpert review of anti-infective therapy
- 2015
A brief overview of the clinical diagnosis of bacteremia in children is provided, focusing on the epidemiology, clinical characteristics, risk factors, antibiotic treatment, outcomes and preventative measures to reduce the incidence of b acteremia and improve morbidity and mortality.
Paediatric meningitis Clinical features and diagnosis
- Medicine, Biology
- 2009
The classic symptoms of meningitis are fever, headache, photophobia and neck stiffness, however, these symptoms can be variable or absent in young children, makingMeningitis difficult to diagnose.
References
SHOWING 1-10 OF 205 REFERENCES
Management of pneumococcal meningitis.
- Medicine, BiologyThe Pediatric infectious disease journal
- 2002
The empiric approach to the child with suspected bacterial meningitis who has received the pneumococcal conjugate vaccine currently remains unchanged and Dexamethasone remains the only adjunctive antiinflammatory therapy to consider.
Clinical presentations, diagnosis, and prognostic factors of bacterial meningitis.
- MedicineInfectious disease clinics of North America
- 1999
Bacterial meningitis in neonates and children.
- MedicineInfectious disease clinics of North America
- 1990
The clinical benefits demonstrated recently with the use of dexamethasone therapy in infants and children with bacterial meningitis underscore the importance of anti-inflammatory therapy to reduce audiologic and neurologic sequelae.
Fifteen years of experience with bacterial meningitis.
- Medicine, BiologyThe Pediatric infectious disease journal
- 1999
A changing pattern in childhood meningitis was observed during the 1981 to 1995 time period, and H. influenzae cases dramatically declined, altering the relative proportions of other pathogens, S. pneumoniae and N. meningitidis.
Dexamethasone in adults with bacterial meningitis.
- MedicineThe New England journal of medicine
- 2003
Background: Even when bacterial meningitis is diagnosed and treated promptly, it causes significant morbidity and mortality in adults. Dexamethasone, which lessens cerebrospinal inflammation, has…
Pathogenesis and pathophysiology of pneumococcal meningitis.
- Medicine, BiologyThe Lancet. Infectious diseases
- 2002
Bacteral Meningitis in Childhood at the Children's Hospital of Pittsburgh: 1988-1998
- MedicineClinical pediatrics
- 2001
The experience at a tertiary-care children's hospital with the occurrence of bacterial meningitis before and after the licensure of the HIB conjugate vaccine is reported.
Vancomycin-tolerant Streptococcus pneumoniae and its clinical significance.
- Medicine, BiologyThe Pediatric infectious disease journal
- 2001
The emergence of vancomycin-resistant pneumococci is a real threat because the inability to eradicate tolerant bacteria may lead to prolonged therapy and failure of antibiotic treatment, and one study suggests that mortality from meningitis caused by tolerant pneumococcus could be increased.
The role of Citrobacter in clinical disease of children: review.
- MedicineClinical infectious diseases : an official publication of the Infectious Diseases Society of America
- 1999
The taxonomy, epidemiology, pathogenesis, diagnosis, treatment, and outcome of citrobacter disease in children are reviewed.