Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins.

@article{Aderem1986BacterialLP,
  title={Bacterial lipopolysaccharides, phorbol myristate acetate, and zymosan induce the myristoylation of specific macrophage proteins.},
  author={Alan A. Aderem and Matthew M. Keum and Ellen Pur{\'e} and Zanvil Alexander Cohn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 16},
  pages={5817-21}
}
We demonstrate stimulus-dependent incorporation of exogenously added [3H]myristic acid into specific macrophage proteins. In control unstimulated cells an 18-kDa protein is the major acylated species. In cells incubated with bacterial lipopolysaccharide (LPS), or its monoacyl glucosamine phosphate derivative, fatty acid is incorporated into proteins with… CONTINUE READING