Bacterial lipopolysaccharide enhances polymorphonuclear leukocyte function independent of changes in intracellular calcium

@article{Klein1990BacterialLE,
  title={Bacterial lipopolysaccharide enhances polymorphonuclear leukocyte function independent of changes in intracellular calcium},
  author={Jon B. Klein and V Gregory Payne and Theresa M. Schepers and Kenneth R Mcleish},
  journal={Inflammation},
  year={1990},
  volume={14},
  pages={599-611}
}
Bacterial lipopolysaccharide (LPS) enhanced expression of C3bi receptors (CR3), phagocytosis of opsonized bacteria, and subsequent hydrogen peroxide (H2O2) production by human polymorphonuclear leukocytes (PMNs). The role of changes in intracellular calcium concentration ([Ca2+]i) in LPS-induced priming was examined by determining the effect of modulators of intracellular calcium on enhanced PMN function, determining the ability of calcium ionophores to reproduce the effects of LPS, and… CONTINUE READING