Bacterial infections in Wegener's granulomatosis: mechanisms potentially involved in autoimmune pathogenesis.

@article{Tadema2011BacterialII,
  title={Bacterial infections in Wegener's granulomatosis: mechanisms potentially involved in autoimmune pathogenesis.},
  author={Henko Tadema and Peter Heeringa and Cees G. M. Kallenberg},
  journal={Current opinion in rheumatology},
  year={2011},
  volume={23 4},
  pages={366-71}
}
PURPOSE OF REVIEW Wegener's granulomatosis is associated with bacterial infection, in particular nasal carriage of Staphylococcus aureus. Infection may play a role in the induction of autoimmunity as well as in the effector phase of the disease. Here, the current hypotheses aiming to explain the link between infections and Wegener's granulomatosis immunopathogenesis are reviewed and discussed. RECENT FINDINGS In recent years, studies suggested that molecular mimicry could play a role in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

Similar Papers

Loading similar papers…