Bacterial ghosts as carriers of protein subunit and DNA-encoded antigens for vaccine applications.

@article{Muhammad2012BacterialGA,
  title={Bacterial ghosts as carriers of protein subunit and DNA-encoded antigens for vaccine applications.},
  author={Abbas Muhammad and Jonathan Champeimont and Ulrike Beate Mayr and Werner Lubitz and Pavol K{\'u}dela},
  journal={Expert review of vaccines},
  year={2012},
  volume={11 1},
  pages={97-116}
}
Bacterial ghosts (BGs) represent vaccine delivery systems gifted with outstanding natural adjuvant properties. BGs are empty cell envelopes of Gram-negative bacteria lacking cytoplasmic content yet retaining all unaltered morphological and structural features of their living counterparts. The intact surface make-up of BGs is easily recognized by professional APCs through pattern-recognition receptors, making them ideal for mucosal administration through oral, ocular, intranasal or aerogenic… CONTINUE READING

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