Bacterial evasion of host immune defense: Yersinia enterocolitica encodes a suppressor for tumor necrosis factor alpha expression.

@article{Beuscher1995BacterialEO,
  title={Bacterial evasion of host immune defense: Yersinia enterocolitica encodes a suppressor for tumor necrosis factor alpha expression.},
  author={Horst Ulrich Beuscher and Franz Roedel and Ake J. Forsberg and Martin Roellinghoff},
  journal={Infection and immunity},
  year={1995},
  volume={63 4},
  pages={1270-7}
}
The ability of the enteropathogenic Yersinia enterocolitica to survive and proliferate in host tissue depends on a 70-kb plasmid known to encode a number of released Yersinia outer proteins that act as virulence factors by inducing cytotoxicity and inhibiting phagocytosis. This study demonstrates that one of the Yersinia outer proteins, the 41-kDa YopB, suppresses the production of tumor necrosis factor alpha (TNF-alpha), a macrophage-derived cytokine with central roles in the regulation of… CONTINUE READING

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Transcriptional and translational regulation of IL-1a and IL-1b account for the control of IL-1 in experimen

  • U. P. Rausch, M. Jordan, +5 authors H. U. Beuscher
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  • 1994

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