Bacterial endotoxin and infection cause behavioural hypothermia in infant mice.

Abstract

1. When placed in a temperature gradient, 3-10 day old mice injected with living Escherichia coli or with E. coli endotoxin, select 2-3 degrees C lower temperatures than their litter-mate controls injected with saline. 2. At the lower selected temperature (32 degrees C) young mouse pups resist bacterial infection for longer and tolerate higher doses of… (More)

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