Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis.

@article{Ibrahim2008BacterialEI,
  title={Bacterial endosymbiosis is widely present among zygomycetes but does not contribute to the pathogenesis of mucormycosis.},
  author={Ashraf S Ibrahim and Teclegiorgis Gebremariam and Mingfu Liu and Georgios Chamilos and Dimitrios Kontoyiannis and Richard Mink and Kyung J. Kwon-Chung and Yue Fu and Christopher D. Skory and John E. Edwards and Brad J. Spellberg},
  journal={The Journal of infectious diseases},
  year={2008},
  volume={198 7},
  pages={1083-90}
}
Environmental isolates of the fungus Rhizopus have been shown to harbor a bacterial endosymbiont (Burkholderia) that produces rhixozin, a plant mycotoxin. We sought to define the role of rhizoxin production by endosymbionts in the pathogenesis of mucormycosis. Endosymbiotic bacteria were identified by polymerase chain reaction in 15 (54%) of 28 clinical isolates of Zygomycetes, with 33% of the bacterial strains showing 87% identity to Burkholderia 16S rDNA. The presence of rhizoxin in myclial… CONTINUE READING

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