Bacterial control of host gene expression through RNA polymerase II.

@article{Lutay2013BacterialCO,
  title={Bacterial control of host gene expression through RNA polymerase II.},
  author={Nataliya Lutay and In{\`e}s Ambite and Jenny Gr{\"o}nberg Hernandez and Gustav Rydstr{\"o}m and Brynd{\'i}s Ragnarsd{\'o}ttir and Manoj Puthia and Aftab Nadeem and Jingyao Zhang and P. -Ch. Storm and Ulrich Dobrindt and Bj{\"o}rn Wullt and Catharina Svanborg},
  journal={The Journal of clinical investigation},
  year={2013},
  volume={123 6},
  pages={2366-79}
}
The normal flora furnishes the host with ecological barriers that prevent pathogen attack while maintaining tissue homeostasis. Urinary tract infections (UTIs) constitute a highly relevant model of microbial adaptation in which some patients infected with Escherichia coli develop acute pyelonephritis, while other patients with bacteriuria exhibit an asymptomatic carrier state similar to bacterial commensalism. It remains unclear if the lack of destructive inflammation merely reflects low… CONTINUE READING
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