Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation.

@article{Moxon2006BacterialCL,
  title={Bacterial contingency loci: the role of simple sequence DNA repeats in bacterial adaptation.},
  author={Richard A Moxon and Chris D Bayliss and Derek W Hood},
  journal={Annual review of genetics},
  year={2006},
  volume={40},
  pages={307-33}
}
Bacterial pathogens face stringent challenges to their survival because of the many unpredictable, often precipitate, and dynamic changes that occur in the host environment or in the process of transmission from one host to another. Bacterial adaptation to their hosts involves either a mechanism for sensing and responding to external changes or the selection of variants that arise through mutation. Here we review how bacterial pathogens exploit localized hypermutation, through polymerase… CONTINUE READING

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