Bacterial cis-2-unsaturated fatty acids found in the cystic fibrosis airway modulate virulence and persistence of Pseudomonas aeruginosa

@article{Twomey2012BacterialCF,
  title={Bacterial cis-2-unsaturated fatty acids found in the cystic fibrosis airway modulate virulence and persistence of Pseudomonas aeruginosa},
  author={Kate B. Twomey and Oisin J. O'Connell and Yvonne McCarthy and John Maxwell Dow and George A O'Toole and Barry J. Plant and Robert Patrick Ryan},
  journal={The ISME Journal},
  year={2012},
  volume={6},
  pages={939-950}
}
There is an increasing appreciation of the polymicrobial nature of many bacterial infections such as those associated with cystic fibrosis (CF) and of the potentially important role for interspecies interactions in influencing both bacterial virulence and response to therapy. Patients with CF are often co-infected with Pseudomonas aeruginosa and other pathogens including Burkholderia cenocepacia and Stenotrophomonas maltophilia. These latter bacteria produce signal molecules of the diffusible… CONTINUE READING

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