Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals

@inproceedings{Stokes2015BacterialAF,
  title={Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals},
  author={Bethany A. Stokes and Shruti Yadav and Upasana Shokal and L Courtney Smith and Ioannis Eleftherianos},
  booktitle={Front. Microbiol.},
  year={2015}
}
In response to bacterial and fungal infections in insects and mammals, distinct families of innate immune pattern recognition receptors (PRRs) initiate highly complex intracellular signaling cascades. Those cascades induce a variety of immune functions that restrain the spread of microbes in the host. Insect and mammalian innate immune receptors include molecules that recognize conserved microbial molecular patterns. Innate immune recognition leads to the recruitment of adaptor molecules… CONTINUE READING
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CD 14 is required for MyD 88independent LPS signaling

  • Z. Jiang, P. George, X. Du, L. Shamel, S. Sovath, S. Mudd
  • Nat . Immunol .
  • 2005
Highly Influential
11 Excerpts

Drosophila Toll is acti

  • J. Reichhart, J. Hoffman, J. Royet
  • 2001
Highly Influential
4 Excerpts

Identification of the first invertebrate interleukin JAK / STAT receptor , the Drosophila gene domeless

  • S. Brown, N. Hu, J. Hombria
  • Curr . Biol .
  • 2001
Highly Influential
4 Excerpts

Bacterial and fungal pattern recognition receptors in homologous innate signaling pathways of insects and mammals

  • BA Stokes, S Yadav, U Shokal, LC Smith, I Eleftherianos
  • Front. Microbiol. 6:19
  • 2015

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