Bacterial acetone and butanol production by industrial fermentation in the Soviet Union: use of hydrolyzed agricultural waste for biorefinery

  title={Bacterial acetone and butanol production by industrial fermentation in the Soviet Union: use of hydrolyzed agricultural waste for biorefinery},
  author={Vladimir V. Zverlov and Oksana V Berezina and Galina A Velikodvorskaya and Wolfgang H. Schwarz},
  journal={Applied Microbiology and Biotechnology},
Clostridial acetone–butanol fermentation from renewable carbohydrates used to be the largest biotechnological process second only to yeast ethanol fermentation and the largest process ever run under sterile conditions. With the rising prices for mineral oil, it has now the economical and technological potential to replace petrochemistry for the production of fuels from renewable resources. Various methods for using non-food biomass such as cellulose and hemicellulose in agricultural products… 

Fermentative butanol production by clostridia

This article reviews biotechnological production of butanol by clostridia and some relevant fermentation and downstream processes and the strategies for strain improvement by metabolic engineering and further requirements to make fermentative butanol production a successful industrial process.

Recent progress on industrial fermentative production of acetone–butanol–ethanol by Clostridium acetobutylicum in China

Current work in strain development, the continuous fermentation process, solvent recovery, and economic evaluation of ABE process in China are reviewed to find out if it could again be potentially competitive with chemical synthesis.

Production of Biobutanol from inulin-rich biomass and industrial food processing wastes

Inflation of crude oil prices, diminishing oil resources and increasing environmental concerns have accelerated the search for renewable alternatives for gasoline. In recent years, biobutanol has

Butanol, ‘a superior biofuel’ production from agricultural residues (renewable biomass): recent progress in technology

This article reviews bioconversion of plant materials such as wheat straw (WS), corn stover (CS), barley straw (BS), and switchgrass (SG) to butanol and process technology that converts these

Cellulosic Butanol Biorefinery: Production of Biobutanol from High Solid Loadings of Sweet Sorghum Bagasse—Simultaneous Saccharification, Fermentation, and Product Recovery

Butanol was produced commercially from cornstarch and sugarcane molasses (renewable resources) until 1983, when production of these plants was forced to cease because of unfavorable economics of

Biobutanol Production from Plant Biomass

This paper summarizes the main outcomes of the authors’ original research on obtaining new butanol-producing strains of Clostridium genus, testing different sources of non-food raw material as a substrate for fermentation and a comparison of different methods of biomass pretreatment.

Milling byproducts are an economically viable substrate for butanol production using clostridial ABE fermentation

Wheat milling byproducts are suitable substrates for clostridial ABE fermentation and ABE fermentation plants using wheat red dog as substrate are economically viable, and a profitability analysis was performed for small- to mid-scale Abe fermentation plants that utilize enzymatically pretreated wheat redDog as substrate.

Biobutanol from Lignocellulosic Wastes

The perceived inability to economically provide conventional petroleum to meet the growing energy demands is facing a diverse and broad set of challenges. The major technical and commercial drawbacks



New insights and novel developments in clostridial acetone/butanol/isopropanol fermentation

  • P. Dürre
  • Biology
    Applied Microbiology and Biotechnology
  • 1998
A reintroduction of acetone/butanol fermentation on an industrial scale seems to be economically feasible, a view that is supported by a new pilot plant in Austria recently coming into operation.

The acetone-butanol-ethanol fermentation.

An historical recap of the traditional industrial process and culturing practices useful in maintaining viable solvent-producing cultures are included, and new and exciting research on the physiology and genetics of the microorganisms as well as process design are summarized.


A technical description of the large scale biotechnology facilities for biomass conversion at Soustons (Landes, France) is presented. The equipments, designed for versatility and operational

Acetone-butanol fermentation and its variants.

Lignocellulose conversion and the future of fermentation biotechnology

Utilisation of biomass for the supply of energy carriers

This mini-review of several fermentation processes is discussed, starting with the most advanced process of ethanol production, followed by methane production, an established process for waste water purification which is gaining more attention because of the inherent energy production.

Cellulase, Clostridia, and Ethanol

The need for such a process, the cellulases of clostridia, their presence in extracellular complexes or organelles (the cellulosomes), the binding of the cellulosome to cellulose and to the cell surface, cellulase genetics, regulation of their synthesis, cocultures, ethanol tolerance, and metabolic pathway engineering for maximizing ethanol yield are discussed.

The economics of acetone-butanol fermentation: theoretical and market considerations.

  • J. Gapes
  • Economics
    Journal of molecular microbiology and biotechnology
  • 2000
Research into the revitalisation of the acetone-butanol fermentation process has shown that the process could once again be run economically in niche markets if run in a relatively small industrial scale processing low-grade agricultural products.

The history of the acetone-butanol project in Austria.

  • J. Gapes
  • Economics
    Journal of molecular microbiology and biotechnology
  • 2000
The present state of the acetone-butanol fermentation is best described as technically and economically difficult but possible in niche markets, and the most likely future is for decentral fermentation facilities processing locally made substrates and selling into niche markets.

Comparative fermentation studies of industrial strains belonging to four species of solvent-producing clostridia.

Solvent yields and concentrations obtained in this study were compared with various published data in the scientific and patent literature and appeared to closely simulate the results obtained in the industrial fermentation process.