Bacterial Small Regulatory RNAs and Hfq Protein

@article{Murina2015BacterialSR,
  title={Bacterial Small Regulatory RNAs and Hfq Protein},
  author={Victoria Murina and Alexey Nikulin},
  journal={Biochemistry (Moscow)},
  year={2015},
  volume={80},
  pages={1647-1654}
}
Small regulatory RNA (sRNA) is a unique noncoding RNA involved in regulation of gene expression in both eukaryotic and bacterial cells. This short review discusses examples of positive and negative translation regulation by sRNAs in bacteria and participation of Hfq in these processes. The importance of structure investigation of nucleotide–protein and RNA–protein complexes for designing a model of Hfq interaction with both mRNA and sRNA simultaneously is demonstrated. 
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Publications referenced by this paper.
SHOWING 1-10 OF 68 REFERENCES

Structure of Escherichia coli Hfq bound to polyriboadenylate RNA.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2009
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Structures of the pleiotropic translational regulator Hfq and an Hfq–RNA complex: a bacterial Sm like protein

M. A. Schumacher, R. F. Pearson, T. Moller, P. Valentin Hansen, R. G. Brennan
  • EMBO J.,
  • 2002
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Hfq binds ribonucleotides in three different RNA-binding sites.

  • Acta crystallographica. Section D, Biological crystallography
  • 2013
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Structural basis for RNA 3'-end recognition by Hfq.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2011
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

The small RNA regulators of Escherichia coli: roles and mechanisms*.

  • Annual review of microbiology
  • 2004
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL