Bacterial Signaling at the Intestinal Epithelial Interface in Inflammation and Cancer

  title={Bacterial Signaling at the Intestinal Epithelial Interface in Inflammation and Cancer},
  author={Olivia I. Coleman and Dirk Haller},
  booktitle={Front. Immunol.},
The gastrointestinal (GI) tract provides a compartmentalized interface with an enormous repertoire of immune and metabolic activities, where the multicellular structure of the mucosa has acquired mechanisms to sense luminal factors, such as nutrients, microbes, and a variety of host-derived and microbial metabolites. The GI tract is colonized by a complex ecosystem of microorganisms, which have developed a highly coevolved relationship with the host's cellular and immune system. Intestinal… CONTINUE READING
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