Bacterial Secretions of Nonpathogenic Escherichia coli Elicit Inflammatory Pathways: a Closer Investigation of Interkingdom Signaling

@article{Zargar2015BacterialSO,
  title={Bacterial Secretions of Nonpathogenic Escherichia coli Elicit Inflammatory Pathways: a Closer Investigation of Interkingdom Signaling},
  author={Amin Zargar and David N. Quan and Karen K Carter and Min Guo and Herman O. Sintim and Gregory F. Payne and William E. Bentley},
  journal={mBio},
  year={2015},
  volume={6}
}
ABSTRACT There have been many studies on the relationship between nonpathogenic bacteria and human epithelial cells; however, the bidirectional effects of the secretomes (secreted substances in which there is no direct bacterium-cell contact) have yet to be fully investigated. In this study, we use a transwell model to explore the transcriptomic effects of bacterial secretions from two different nonpathogenic Escherichia coli strains on the human colonic cell line HCT-8 using next-generation… 
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