Bacteria in sputum of stable severe asthma and increased airway wall thickness

@inproceedings{Zhang2012BacteriaIS,
  title={Bacteria in sputum of stable severe asthma and increased airway wall thickness},
  author={Qingling Zhang and Rowland Oliver Illing and Christopher Kim Ming Hui and Kate Downey and Denis H. Carr and Martin Stearn and Khalid Alshafi and Andrew Menzies-Gow and Nan Zhong and Kian Fan Chung},
  booktitle={Respiratory Research},
  year={2012}
}
BackgroundPatients with chronic asthma have thicker intrapulmonary airways measured on high resolution computed tomography (HRCT). We determined whether the presence of lower airway bacteria was associated with increased airway wall thickness.MethodsIn 56 patients with stable severe asthma, sputum specimens obtained either spontaneously or after induction with hypertonic saline were cultured for bacteria and thoracic HRCT scans obtained. Wall thickness (WT) and area (WA) expressed as a ratio of… CONTINUE READING
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