Bacteria and bacterial toxins as therapeutic agents for solid tumors.

  title={Bacteria and bacterial toxins as therapeutic agents for solid tumors.},
  author={Patrick Michl and Thomas M. Gress},
  journal={Current cancer drug targets},
  volume={4 8},
Patients with advanced solid tumors frequently relapse and succumb to their metastatic disease after developing resistance to conventional treatment modalities such as chemotherapy and radiotherapy. In these patients, novel strategies of targeting widespread tumors are urgently needed. The increasing knowledge of the underlying pathogenetic mechanisms has led to the identification of numerous molecules that are overexpressed in various tumors and accumulate at the cell surface. The use of… CONTINUE READING

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