Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes?

@article{Celli2015BacteriaTE,
  title={Bacteria, the endoplasmic reticulum and the unfolded protein response: friends or foes?},
  author={Jean Celli and Ren{\'e}e M Tsolis},
  journal={Nature Reviews Microbiology},
  year={2015},
  volume={13},
  pages={71-82}
}
The unfolded protein response (UPR) is a cytoprotective response that is aimed at restoring cellular homeostasis following physiological stress exerted on the endoplasmic reticulum (ER), which also invokes innate immune signalling in response to invading microorganisms. Although it has been known for some time that the UPR is modulated by various viruses, recent evidence indicates that it also has multiple roles during bacterial infections. In this Review, we describe how bacteria interact with… CONTINUE READING
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References

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A new paradigm : innate immune sensing of viruses via the unfolded protein response

R. Fronzes, Christie, G. Waksman
Front . Microbiol . • 2014

Crystal structures of the Toll/ interleukin‐1 receptor (TIR) domains from the Brucella protein TcpB and host adaptor TIRAP reveal mechanisms of molecular mimicry

Snyder, A G.
J. Biol • 2014

innate immune sensing of viruses via the unfolded protein response

Smith, J. A. A new paradigm
Front. Microbiol. 5, 222 • 2014

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