Baclofen as an adjuvant analgesic.

@article{Fromm1994BaclofenAA,
  title={Baclofen as an adjuvant analgesic.},
  author={G H Fromm},
  journal={Journal of pain and symptom management},
  year={1994},
  volume={9 8},
  pages={500-9}
}
  • G H Fromm
  • Published 1994 in Journal of pain and symptom management
Baclofen is a gamma-aminobutyric acid (GABA) agonist approved for the treatment of spasticity and commonly used in the management of many types of neuropathic pain. Controlled studies have demonstrated the efficacy of this drug in trigeminal neuralgia. Although its precise mechanism of analgesic action is unknown, it is likely that a drug-induced increase in inhibitory activity is sufficient to interrupt the cascade of neural events that culminates in aberrant activity of wide dynamic range… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

The pharmacotherapy of chronic pain: a review.

Pain research & management • 2006
View 5 Excerpts
Highly Influenced

Clinical Evaluation and Management of Spasticity

Current Clinical Neurology • 2002
View 14 Excerpts
Highly Influenced

Chirality counts?

Pain physician • 2012
View 2 Excerpts

Similar Papers

Loading similar papers…