Backwash Is Hogwash: The Clinical Significance of Ileitis in Ulcerative Colitis
@article{Patil2017BackwashIH, title={Backwash Is Hogwash: The Clinical Significance of Ileitis in Ulcerative Colitis}, author={Deepa T. Patil and Robert D Odze}, journal={The American Journal of Gastroenterology}, year={2017}, volume={112}, pages={1211-1214} }
INTRODUCTION Up to 35% of patients with ulcerative colitis (UC) develop infl ammation in the terminal ileum, which historically, has been attributed to backwash of colonic contents into the terminal ileum, a condition termed “backwash ileitis” (BWI) ( 1–5 ). Th e hypothetical mechanism for this phenomenon is that when infl ammation of the proximal cecum/ileocecal mucosa is severe enough, it may cause malfunction of the ileocecal junction (ICJ) and retrograde fl ow of colonic contents into the…
13 Citations
Microscopic / "Backwash" Ileitis and its Association with Colonic Disease in New Onset Pediatric Ulcerative Colitis.
- MedicineJournal of pediatric gastroenterology and nutrition
- 2019
Patients with new onset ulcerative colitis may have microscopic ileal inflammation at time of diagnosis, even if the terminal ileum appears macroscopically normal, and children with microscopic ilesitis in the context of UC do not need to be reclassified as "indeterminate colitis" or Crohn's disease.
Discrete terminal ileal ulcers in patients diagnosed with ulcerative colitis: clinical significance and natural course
- MedicineBMC Gastroenterology
- 2021
Discrete TI ulcers are more common in patients with UC, compared with the healthy cohort, and no significant clinical impact on disease extension and severity is found.
A Practical Index to Distinguish Backwash Ileitis From Crohn's Terminal Ileitis in MR Enterography.
- MedicineInflammatory bowel diseases
- 2022
Two practical indices introduced in this study showed high specificity to distinguish BWI from CTI, including ileocecal valve patency indices-C and ICPI-T, which can accurately differentiate BWIFrom CTI.
Prognostic Value of Terminal Ileal Inflammation in Patients with Ulcerative Colitis
- Medicine, PsychologyGut and liver
- 2021
For patients with UC in clinical remission, neither terminal ileal lesions nor AOI had significant clinical or predictive value for future relapse.
Clinicopathologic Features and Diagnostic Implications of Pyloric Gland Metaplasia in Intestinal Specimens.
- MedicineThe American journal of surgical pathology
- 2020
In conclusion, intestinal PGM warrants a high suspicion for IBD and specifically CD, however, it should be interpreted with caution, especially in older patients or those with a history of prior intestinal surgery and in colorectal biopsies or specimens lacking severely active inflammation.
Increase in chromogranin A- and serotonin-positive cells in pouch mucosa of patients with ulcerative colitis undergoing proctocolectomy.
- Medicine, BiologyDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
- 2018
Biopsy diagnosis of colitis: an algorithmic approach
- MedicineVirchows Archiv
- 2017
This review will focus on a pattern-based algorithmic approach to evaluating biopsies of patients who present to physicians with signs and symptoms of colitis, to distinguish variations in normal mucosa and biopsy procedure-related artifacts from true inflammatory conditions.
Narrative review of colorectal cancer risk in patients with inflammatory bowel disease
- MedicineDigestive Medicine Research
- 2020
Endoscopic surveillance programs have been implemented and are recommended depending on the risk factors of each patient, it is important to detect early precancerous lesions to perform timely treatment and prevent the development of CRC.
References
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The original description1in 1932 of a granulomatous, ulcerating and stenosing inflammation of the small intestine, denominated regional or terminal ileitis, covered fourteen cases of a uniform…
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Ileitis in Patients with UC may represent a primary extracolonic manifestation of UC in patients with inactive or mild disease and is not due to backwash.