Backward-stochastic-differential-equation approach to modeling of gene expression.

  title={Backward-stochastic-differential-equation approach to modeling of gene expression.},
  author={Evelina Shamarova and Roman A. Chertovskih and Alexandre F. Ramos and Paulo Aguiar},
  journal={Physical review. E},
  volume={95 3-1},
  • Evelina Shamarova, Roman A. Chertovskih, +1 author Paulo Aguiar
  • Published 2017
  • Medicine, Physics, Mathematics, Biology
  • Physical review. E
  • In this article, we introduce a backward method to model stochastic gene expression and protein-level dynamics. The protein amount is regarded as a diffusion process and is described by a backward stochastic differential equation (BSDE). Unlike many other SDE techniques proposed in the literature, the BSDE method is backward in time; that is, instead of initial conditions it requires the specification of end-point ("final") conditions, in addition to the model parametrization. To validate our… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Explore Further: Topics Discussed in This Paper


    Publications referenced by this paper.